Synonyms |
7-ethyl-10-hydro(20)s-camptothecin ; SN38 |
| Brief introduction |
7-ethyl-10-hydroxycamptothecin can make topoisomerase_I inactive,
lead DNA to irreversible single chain break, cell death and
have no crossed medicine-resistant with 5_Fu,Cisplatin. |
Structure |
|
Molecular weight |
392.34 |
| Molecular Formula |
C22H20N5O2 |
| Property |
buff crystal powder. melting point:230~237°C |
|